ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that regulate genes involved in energy metabolism and inflammation. For biological activity, PPARs require cognate lipid ligands, heterodimerization with retinoic × receptors, and coactivation by PPAR-γ coactivator-1α...

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Hauptverfasser: Haemmerle, Guenter, Moustafa, Tarek, Woelkart, Gerald, Büttner, Sabrina, Schmidt, Albrecht, van de Weijer, Tineke, Hesselink, Matthijs, Jaeger, Doris, Kienesberger, Petra C, Zierler, Kathrin, Schreiber, Renate, Eichmann, Thomas, Kolb, Dagmar, Kotzbeck, Petra, Schweiger, Martina, Kumari, Manju, Eder, Sandra, Schoiswohl, Gabriele, Wongsiriroj, Nuttaporn, Pollak, Nina M, Radner, Franz P W, Preiss-Landl, Karina, Kolbe, Thomas, Rülicke, Thomas, Pieske, Burkert, Trauner, Michael, Lass, Achim, Zimmermann, Robert, Hoefler, Gerald, Cinti, Saverio, Kershaw, Erin E, Schrauwen, Patrick, Madeo, Frank, Mayer, Bernd, Zechner, Rudolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244833/
https://ncbi.nlm.nih.gov/pubmed/21857651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2439
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