ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that regulate genes involved in energy metabolism and inflammation. For biological activity, PPARs require cognate lipid ligands, heterodimerization with retinoic × receptors, and coactivation by PPAR-γ coactivator-1α...

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Main Authors: Haemmerle, Guenter, Moustafa, Tarek, Woelkart, Gerald, Büttner, Sabrina, Schmidt, Albrecht, van de Weijer, Tineke, Hesselink, Matthijs, Jaeger, Doris, Kienesberger, Petra C, Zierler, Kathrin, Schreiber, Renate, Eichmann, Thomas, Kolb, Dagmar, Kotzbeck, Petra, Schweiger, Martina, Kumari, Manju, Eder, Sandra, Schoiswohl, Gabriele, Wongsiriroj, Nuttaporn, Pollak, Nina M, Radner, Franz P W, Preiss-Landl, Karina, Kolbe, Thomas, Rülicke, Thomas, Pieske, Burkert, Trauner, Michael, Lass, Achim, Zimmermann, Robert, Hoefler, Gerald, Cinti, Saverio, Kershaw, Erin E, Schrauwen, Patrick, Madeo, Frank, Mayer, Bernd, Zechner, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244833/
https://ncbi.nlm.nih.gov/pubmed/21857651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2439
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