Automated Analysis of Protein Expression and Gene Amplification within the Same Cells of Paraffin-Embedded Tumour Tissue

Background: The simultaneous detection of protein expression and gene copy number changes in patient samples, like paraffin-embedded tissue sections, is challenging since the procedures of immunohistochemistry (IHC) and Fluorescence in situ Hybridization (FISH) negatively influence each other which...

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Autori principali: Gaiser, Timo, Berroa-Garcia, Lissa, Kemmerling, Ralf, Dutta, Aparajita, Ried, Thomas, Heselmeyer-Haddad, Kerstin
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOS Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244818/
https://ncbi.nlm.nih.gov/pubmed/20966547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ACP-CLO-2010-0532
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