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RIP1-mediated regulation of lymphocyte survival and death responses
RIP1 is an adaptor serine/threonine kinase associated with the signaling complex of death receptors (DRs) including Fas, TNFR1, and TRAIL-Rs which can initiate apoptosis. While DRs are dispensable throughout development, RIP1 deletion results in perinatal lethality. The developmental defect caused b...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244575/ https://ncbi.nlm.nih.gov/pubmed/22038529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-011-8249-3 |
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