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Comparison of IRES and F2A-Based Locus-Specific Multicistronic Expression in Stable Mouse Lines

Efficient and stoichiometric expression of genes concatenated by bi- or multi-cistronic vectors has become an invaluable tool not only in basic biology to track and visualize proteins in vivo, but also for vaccine development and in the clinics for gene therapy. To adequately compare, in vivo, the e...

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Bibliografske podrobnosti
Main Authors: Chan, Hsiao Yun, Sivakamasundari, Xing, Xing, Kraus, Petra, Yap, Sook Peng, Ng, Patricia, Lim, Siew Lan, Lufkin, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244433/
https://ncbi.nlm.nih.gov/pubmed/22216134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028885
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