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A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development

Pax1 and Pax9 play redundant, synergistic functions in the patterning and differentiation of the sclerotomal cells that give rise to the vertebral bodies and intervertebral discs (IVD) of the axial skeleton. They are conserved in mice and humans, whereby mutation/deficiency of human PAX1/PAX9 has be...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Sivakamasundari, V., Kraus, Petra, Sun, Wenjie, Hu, Xiaoming, Lim, Siew Lan, Prabhakar, Shyam, Lufkin, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312110/
https://ncbi.nlm.nih.gov/pubmed/28011632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.023218
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