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KRAS Mutations Testing in Colorectal Carcinoma Patients in Italy: From Guidelines to External Quality Assessment

BACKGROUND: Monoclonal antibodies directed against the epidermal growth factor receptor (EGFR) have been approved for the treatment of patients with metastatic colorectal carcinoma (mCRC) that do not carry KRAS mutations. Therefore, KRAS testing has become mandatory to chose the most appropriate the...

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Detalhes bibliográficos
Main Authors: Normanno, Nicola, Pinto, Carmine, Castiglione, Francesca, Bardelli, Alberto, Gambacorta, Marcello, Botti, Gerardo, Nappi, Oscar, Siena, Salvatore, Ciardiello, Fortunato, Taddei, GianLuigi, Marchetti, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244430/
https://ncbi.nlm.nih.gov/pubmed/22216189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029146
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