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The Plasmodium falciparum Malaria M1 Alanyl Aminopeptidase (PfA-M1): Insights of Catalytic Mechanism and Function from MD Simulations

Malaria caused by several species of Plasmodium is major parasitic disease of humans, causing 1–3 million deaths worldwide annually. The widespread resistance of the human parasite to current drug therapies is of major concern making the identification of new drug targets urgent. While the parasite...

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Bibliografski detalji
Glavni autori: Jones, Peter M., Robinson, Mark W., Dalton, John P., George, Anthony M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244404/
https://ncbi.nlm.nih.gov/pubmed/22205955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028589
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