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A comparative analysis of HIV-specific mucosal/systemic T cell immunity and avidity following rDNA/rFPV and poxvirus–poxvirus prime boost immunisations

In this study we have firstly compared a range of recombinant DNA poxvirus prime-boost immunisation strategies and shown that combined intramuscular (i.m.) 2×DNA-HIV/intranasal (i.n.) 2×FPV-HIV prime-boost immunisation can generate high-level of HIV-specific systemic (spleen) and mucosal (genito-rec...

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Detalhes bibliográficos
Main Authors: Ranasinghe, Charani, Eyers, Fiona, Stambas, John, Boyle, David B., Ramshaw, Ian A., Ramsay, Alistair J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244379/
https://ncbi.nlm.nih.gov/pubmed/21352941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.01.106
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