Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome

Epidermal Langerhans cells (LCs) extend dendrites through tight junctions (TJs) to survey the skin surface, but their immunological contribution in vivo remains elusive. We show that LCs were essential for inducing IgG(1) responses to patch-immunized ovalbumin in mice that lacked skin dendritic cell...

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Библиографические подробности
Главные авторы: Ouchi, Takeshi, Kubo, Akiharu, Yokouchi, Mariko, Adachi, Takeya, Kobayashi, Tetsuro, Kitashima, Daniela Y., Fujii, Hideki, Clausen, Björn E., Koyasu, Shigeo, Amagai, Masayuki, Nagao, Keisuke
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2011
Предметы:
Brief Definitive Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244045/
https://ncbi.nlm.nih.gov/pubmed/22143886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111718
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