Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome

Epidermal Langerhans cells (LCs) extend dendrites through tight junctions (TJs) to survey the skin surface, but their immunological contribution in vivo remains elusive. We show that LCs were essential for inducing IgG(1) responses to patch-immunized ovalbumin in mice that lacked skin dendritic cell...

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Hlavní autoři: Ouchi, Takeshi, Kubo, Akiharu, Yokouchi, Mariko, Adachi, Takeya, Kobayashi, Tetsuro, Kitashima, Daniela Y., Fujii, Hideki, Clausen, Björn E., Koyasu, Shigeo, Amagai, Masayuki, Nagao, Keisuke
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244045/
https://ncbi.nlm.nih.gov/pubmed/22143886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111718
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