Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome

Epidermal Langerhans cells (LCs) extend dendrites through tight junctions (TJs) to survey the skin surface, but their immunological contribution in vivo remains elusive. We show that LCs were essential for inducing IgG(1) responses to patch-immunized ovalbumin in mice that lacked skin dendritic cell...

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Bibliografiske detaljer
Main Authors: Ouchi, Takeshi, Kubo, Akiharu, Yokouchi, Mariko, Adachi, Takeya, Kobayashi, Tetsuro, Kitashima, Daniela Y., Fujii, Hideki, Clausen, Björn E., Koyasu, Shigeo, Amagai, Masayuki, Nagao, Keisuke
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244045/
https://ncbi.nlm.nih.gov/pubmed/22143886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111718
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