A genomic storm in critically injured humans

Human survival from injury requires an appropriate inflammatory and immune response. We describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well as in healthy subjects receiving low-dose bacterial endotoxin, and show that these severe stresses produce a global re...

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Bibliografiske detaljer
Main Authors: Xiao, Wenzhong, Mindrinos, Michael N., Seok, Junhee, Cuschieri, Joseph, Cuenca, Alex G., Gao, Hong, Hayden, Douglas L., Hennessy, Laura, Moore, Ernest E., Minei, Joseph P., Bankey, Paul E., Johnson, Jeffrey L., Sperry, Jason, Nathens, Avery B., Billiar, Timothy R., West, Michael A., Brownstein, Bernard H., Mason, Philip H., Baker, Henry V., Finnerty, Celeste C., Jeschke, Marc G., López, M. Cecilia, Klein, Matthew B., Gamelli, Richard L., Gibran, Nicole S., Arnoldo, Brett, Xu, Weihong, Zhang, Yuping, Calvano, Steven E., McDonald-Smith, Grace P., Schoenfeld, David A., Storey, John D., Cobb, J. Perren, Warren, H. Shaw, Moldawer, Lyle L., Herndon, David N., Lowry, Stephen F., Maier, Ronald V., Davis, Ronald W., Tompkins, Ronald G.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244029/
https://ncbi.nlm.nih.gov/pubmed/22110166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111354
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