A genomic storm in critically injured humans

Human survival from injury requires an appropriate inflammatory and immune response. We describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well as in healthy subjects receiving low-dose bacterial endotoxin, and show that these severe stresses produce a global re...

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Main Authors: Xiao, Wenzhong, Mindrinos, Michael N., Seok, Junhee, Cuschieri, Joseph, Cuenca, Alex G., Gao, Hong, Hayden, Douglas L., Hennessy, Laura, Moore, Ernest E., Minei, Joseph P., Bankey, Paul E., Johnson, Jeffrey L., Sperry, Jason, Nathens, Avery B., Billiar, Timothy R., West, Michael A., Brownstein, Bernard H., Mason, Philip H., Baker, Henry V., Finnerty, Celeste C., Jeschke, Marc G., López, M. Cecilia, Klein, Matthew B., Gamelli, Richard L., Gibran, Nicole S., Arnoldo, Brett, Xu, Weihong, Zhang, Yuping, Calvano, Steven E., McDonald-Smith, Grace P., Schoenfeld, David A., Storey, John D., Cobb, J. Perren, Warren, H. Shaw, Moldawer, Lyle L., Herndon, David N., Lowry, Stephen F., Maier, Ronald V., Davis, Ronald W., Tompkins, Ronald G.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Brief Definitive Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244029/
https://ncbi.nlm.nih.gov/pubmed/22110166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111354
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