A genomic storm in critically injured humans

Human survival from injury requires an appropriate inflammatory and immune response. We describe the circulating leukocyte transcriptome after severe trauma and burn injury, as well as in healthy subjects receiving low-dose bacterial endotoxin, and show that these severe stresses produce a global re...

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Detalhes bibliográficos
Main Authors: Xiao, Wenzhong, Mindrinos, Michael N., Seok, Junhee, Cuschieri, Joseph, Cuenca, Alex G., Gao, Hong, Hayden, Douglas L., Hennessy, Laura, Moore, Ernest E., Minei, Joseph P., Bankey, Paul E., Johnson, Jeffrey L., Sperry, Jason, Nathens, Avery B., Billiar, Timothy R., West, Michael A., Brownstein, Bernard H., Mason, Philip H., Baker, Henry V., Finnerty, Celeste C., Jeschke, Marc G., López, M. Cecilia, Klein, Matthew B., Gamelli, Richard L., Gibran, Nicole S., Arnoldo, Brett, Xu, Weihong, Zhang, Yuping, Calvano, Steven E., McDonald-Smith, Grace P., Schoenfeld, David A., Storey, John D., Cobb, J. Perren, Warren, H. Shaw, Moldawer, Lyle L., Herndon, David N., Lowry, Stephen F., Maier, Ronald V., Davis, Ronald W., Tompkins, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244029/
https://ncbi.nlm.nih.gov/pubmed/22110166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111354
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