Methods for high throughput validation of amplified fragment pools of BAC DNA for constructing high resolution CGH arrays

BACKGROUND: The recent development of array based comparative genomic hybridization (CGH) technology provides improved resolution for detection of genomic DNA copy number alterations. In array CGH, generating spotting solution is a multi-step process where bacterial artificial chromosome (BAC) clone...

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Bibliografske podrobnosti
Main Authors: Watson, Spencer K, deLeeuw, Ronald J, Ishkanian, Adrian S, Malloff, Chad A, Lam, Wan L
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2004
Teme:
Methodology Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC324397/
https://ncbi.nlm.nih.gov/pubmed/14723794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-5-6
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