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Methods for high throughput validation of amplified fragment pools of BAC DNA for constructing high resolution CGH arrays

BACKGROUND: The recent development of array based comparative genomic hybridization (CGH) technology provides improved resolution for detection of genomic DNA copy number alterations. In array CGH, generating spotting solution is a multi-step process where bacterial artificial chromosome (BAC) clone...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Watson, Spencer K, deLeeuw, Ronald J, Ishkanian, Adrian S, Malloff, Chad A, Lam, Wan L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2004
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC324397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14723794/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2164-5-6
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