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Reversible Epigenetic Modifications of the Two Cardiac Myosin Heavy Chain Genes During Changes in Expression

The two genes of the cardiac myosin heavy chain (MHC) locus—alpha-MHC (aMHC) and beta-MHC (bMHC)—are reciprocally regulated in the mouse ventricle during development and in adult conditions such as hypothyroidism and pathological cardiac hypertrophy. Their expressions are under the control of thyroi...

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Detalhes bibliográficos
Main Authors: Pandya, Kumar, Pulli, Benjamin, Bultman, Scott, Smithies, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243912/
https://ncbi.nlm.nih.gov/pubmed/21526716
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