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Cardiac myosin heavy chain gene regulation by thyroid hormone involves altered histone modifications

The antithetical regulation of cardiac α- and β-myosin heavy chain (MHC) genes by thyroid hormone (T(3)) is not well understood but appears to involve thyroid hormone interaction with its nuclear receptor and MHC promoters as well as cis-acting noncoding regulatory RNA (ncRNA). Both of these phenome...

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Hlavní autoři: Haddad, F., Jiang, W., Bodell, P. W., Qin, A. X., Baldwin, K. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006294/
https://ncbi.nlm.nih.gov/pubmed/20833952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00644.2010
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