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Cardiac myosin heavy chain gene regulation by thyroid hormone involves altered histone modifications

The antithetical regulation of cardiac α- and β-myosin heavy chain (MHC) genes by thyroid hormone (T(3)) is not well understood but appears to involve thyroid hormone interaction with its nuclear receptor and MHC promoters as well as cis-acting noncoding regulatory RNA (ncRNA). Both of these phenome...

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Библиографические подробности
Главные авторы: Haddad, F., Jiang, W., Bodell, P. W., Qin, A. X., Baldwin, K. M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006294/
https://ncbi.nlm.nih.gov/pubmed/20833952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00644.2010
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