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Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues.

Sodium bisulfite is a mutagen which can specifically deaminate more than 96% of the cytosine residues in single-stranded DNA via formation of a 5,6-dihydrocytosine-6-sulfonate intermediate. Under the same reaction conditions, only 2-3% of the 5-methylcytosine (m5Cyt) residues in single-stranded XP-1...

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Bibliografske podrobnosti
Main Authors: Wang, R Y, Gehrke, C W, Ehrlich, M
Format: Artigo
Jezik:Inglês
Izdano: 1980
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC324387/
https://ncbi.nlm.nih.gov/pubmed/7443525
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