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Ribose 5-Phosphate Glycation Reduces Cytochrome c Respiratory Activity and Membrane Affinity()

Spontaneous glycation of bovine heart cytochrome c (cyt c) by the sugar ribose 5-phosphate (R5P) decreases the ability of the heme protein to transfer electrons in the respiratory pathway and to bind to membranes. Trypsin fragmentation studies suggest the preferential sites of glycation include Lys7...

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Detalhes bibliográficos
Main Authors: Hildick-Smith, Gordon J., Downey, Michael C., Gretebeck, Lisa M., Gersten, Rebecca A., Sandwick, Roger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243802/
https://ncbi.nlm.nih.gov/pubmed/22091532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2012977
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