Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens

New chemical entities are desperately needed that overcome the limitations of existing drugs for neglected diseases. Screening a diverse library of 10,000 drug-like compounds against 7 neglected disease pathogens resulted in an integrated dataset of 744 hits. We discuss the prioritization of these h...

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Detalhes bibliográficos
Main Authors: Nwaka, Solomon, Besson, Dominique, Ramirez, Bernadette, Maes, Louis, Matheeussen, An, Bickle, Quentin, Mansour, Nuha R., Yousif, Fouad, Townson, Simon, Gokool, Suzanne, Cho-Ngwa, Fidelis, Samje, Moses, Misra-Bhattacharya, Shailja, Murthy, P. K., Fakorede, Foluke, Paris, Jean-Marc, Yeates, Clive, Ridley, Robert, Van Voorhis, Wesley C., Geary, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243694/
https://ncbi.nlm.nih.gov/pubmed/22247786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001412
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