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Using Amino Acid Correlation and Community Detection Algorithms to Identify Functional Determinants in Protein Families

Correlated mutation analysis has a long history of interesting applications, mostly in the detection of contact pairs in protein structures. Based on previous observations that, if properly assessed, amino acid correlation data can also provide insights about functional sub-classes in a protein fami...

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Bibliografske podrobnosti
Main Authors: Bleicher, Lucas, Lemke, Ney, Garratt, Richard Charles
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243672/
https://ncbi.nlm.nih.gov/pubmed/22205928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027786
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