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Molecular Determinants of Ivermectin Sensitivity at the Glycine Receptor Chloride Channel
Ivermectin is an anthelmintic drug that works by activating glutamate-gated chloride channel receptors (GluClRs) in nematode parasites. GluClRs belong to the Cys-loop receptor family that also includes glycine receptor (GlyR) chloride channels. GluClRs and A288G mutant GlyRs are both activated by lo...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243547/ https://ncbi.nlm.nih.gov/pubmed/22033924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.262634 |
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