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Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Ivermectin is an anthelmintic drug that works by inhibiting neuronal activity and muscular contractility in arthropods and nematodes. It works by activating glutamate-gated chloride channels (GluClRs) at nanomolar concentrations. These receptors, found exclusively in invertebrates, belong to the pen...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345530/ https://ncbi.nlm.nih.gov/pubmed/22586367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00060 |
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