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α-Synuclein Stimulates a Dopamine Transporter-dependent Chloride Current and Modulates the Activity of the Transporter

Dysregulation of dopamine (DA) homeostasis is implicated in neurodegenerative diseases, drug addiction, and neuropsychiatric disorders. The neuronal plasma membrane dopamine transporter (DAT) is essential for the maintenance of DA homeostasis in the brain. α-Synuclein is a 140-amino acid protein tha...

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書目詳細資料
Main Authors: Swant, Jarod, Goodwin, J. Shawn, North, Ashley, Ali, Ahmad Abdul, Gamble-George, Joyonna, Chirwa, Sanika, Khoshbouei, Habibeh
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243541/
https://ncbi.nlm.nih.gov/pubmed/21990355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241232
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