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Myocardin-related Transcription Factor-A Complexes Activate Type I Collagen Expression in Lung Fibroblasts
Pulmonary fibrosis is characterized by the excessive deposition of a collagen-rich extracellular matrix. The accumulation of collagen within the lung interstitium leads to impaired respiratory function. Furthermore, smooth muscle actin-positive myofibroblasts within the fibrotic lung contribute to d...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243519/ https://ncbi.nlm.nih.gov/pubmed/22049076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.276931 |
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