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Choline phosphorylation and regulation of transcription of choline kinase α in hypoxia
Choline kinase catalyzes the phosphorylation of choline, the first step of phospholipid synthesis. Increased phosphorylation of choline is a hallmark characteristic of the malignant phenotype in a variety of neoplasms. However, in hypoxic cancer cells, choline phosphorylation is decreased. To unders...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3243471/ https://ncbi.nlm.nih.gov/pubmed/22025560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021030 |
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