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How selection forces dictate the variant surface antigens used by malaria parasites

Red blood cells infected by the malaria parasite Plasmodium falciparum express variant surface antigens (VSAs) that evade host immunity and allow the parasites to persist in the human population. There exist many different VSAs and the differential expression of these VSAs is associated with the vir...

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Autori principali: Severins, Maite, Klinkenberg, Don, Heesterbeek, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243386/
https://ncbi.nlm.nih.gov/pubmed/21733875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0239
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