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Variant surface antigens of malaria parasites: functional and evolutionary insights from comparative gene family classification and analysis

BACKGROUND: Plasmodium parasites, the causative agents of malaria, express many variant antigens on cell surfaces. Variant surface antigens (VSAs) are typically organized into large subtelomeric gene families that play critical roles in virulence and immune evasion. Many important aspects of VSA fun...

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Autori principali: Frech, Christian, Chen, Nansheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747859/
https://ncbi.nlm.nih.gov/pubmed/23805789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-427
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