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The Effect of Reference Panels and Software Tools on Genotype Imputation

Genotype imputation is increasingly employed in genome-wide association studies, particularly for integrative and cross-platform analysis. Several imputation algorithms use reference panels with a larger set of genotyped markers to infer genotypes at ungenotyped marker locations. Our objective was t...

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Autores principales: Nho, Kwangsik, Shen, Li, Kim, Sungeun, Swaminathan, Shanker, Risacher, Shannon L., Saykin, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Informatics Association 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243280/
https://ncbi.nlm.nih.gov/pubmed/22195161
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