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Evaluating De Novo Locus-Disease Discoveries in GWAS Using the Signal-to-Noise Ratio

A genome-wide association study (GWAS) involves examining representative SNPs obtained using high throughput technologies. A GWAS data set can entail a million SNPs and may soon entail many millions. In a GWAS researchers often investigate the correlation of each SNP with a disease. With so many hyp...

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Bibliografske podrobnosti
Main Authors: Jiang, Xia, Barmada, M. Michael, Becich, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: American Medical Informatics Association 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243170/
https://ncbi.nlm.nih.gov/pubmed/22195117
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