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A photoactivatable small-molecule inhibitor for light-controlled spatiotemporal regulation of Rho kinase in live embryos

To uncover the molecular mechanisms of embryonic development, the ideal loss-of-function strategy would be capable of targeting specific regions of the living embryo with both temporal and spatial precision. To this end, we have developed a novel pharmacological agent that can be light activated to...

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Detaylı Bibliyografya
Asıl Yazarlar: Morckel, Allison R., Lusic, Hrvoje, Farzana, Laila, Yoder, Jeffrey A., Deiters, Alexander, Nascone-Yoder, Nanette M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243101/
https://ncbi.nlm.nih.gov/pubmed/22186732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.072165
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