Unusually Strong Temperature Dependence of P2X3 Receptor Traffic to the Plasma Membrane

ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, suggesting a role for these receptors in analgesic effects of cooling. Since sustained responsiveness depends on receptor t...

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Bibliographic Details
Main Authors: Pryazhnikov, E., Fayuk, D., Niittykoski, M., Giniatullin, Rashid, Khiroug, Leonard
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2011
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243083/
https://ncbi.nlm.nih.gov/pubmed/22194716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2011.00027
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