Phase 2 Clinical Trial of Intrathecal Topotecan in Children with Refractory Leptomeningeal Leukemia: A Children’s Oncology Group Trial (P9962)

PURPOSE: We performed a phase 2 study in children with recurrent or refractory leptomeningeal leukemia to determine the objective response rate after treatment with intrathecal topotecan. PATIENTS AND METHODS: Patients received age-adjusted intrathecal topotecan (0.4 mg/dose for patients > 3 year...

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Hlavní autoři: Potter, Samara L. Poplack, Berg, Stacey, Ingle, Ashish Mark, Krailo, Mark, Adamson, Peter C., Blaney, Susan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242923/
https://ncbi.nlm.nih.gov/pubmed/21910214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.23317
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