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Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays

Chikungunya virus (CHIKV), an alphavirus, has recently caused epidemic outbreaks and is therefore considered a re-emerging pathogen for which no effective treatment is available. In this study, a CHIKV replicon containing the virus replicase proteins together with puromycin acetyltransferase, EGFP a...

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Главные авторы: Pohjala, Leena, Utt, Age, Varjak, Margus, Lulla, Aleksei, Merits, Andres, Ahola, Tero, Tammela, Päivi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242765/
https://ncbi.nlm.nih.gov/pubmed/22205980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028923
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