Application of a Novel Score Test for Genetic Association Incorporating Gene-Gene Interaction Suggests Functionality for Prostate Cancer Susceptibility Regions

AIMS: We introduce an innovative multilocus test for disease association. It is an extension of an existing score test that gains power over alternative methods by incorporating a parsimonious one-degree-of-freedom model for interaction. We use our method in applications designed to detect interacti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ciampa, Julia, Yeager, Meredith, Jacobs, Kevin, Thun, Michael J., Gapstur, Susan, Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie J., Giovannucci, Edward, Willett, Walter C., Cancel-Tassin, Geraldine, Cussenot, Olivier, Valeri, Antoine, Hunter, David, Hoover, Robert, Thomas, Gilles, Chanock, Stephen, Holmes, Chris, Chatterjee, Nilanjan
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242702/
https://ncbi.nlm.nih.gov/pubmed/22086326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000331222
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados