Selective Therapeutic Targeting of the Anaplastic Lymphoma Kinase With Liposomal siRNA Induces Apoptosis and Inhibits Angiogenesis in Neuroblastoma

The anaplastic lymphoma kinase (ALK) is a tyrosine kinase receptor that is involved in the pathogenesis of different types of human cancers, including neuroblastoma (NB). In NB, ALK overexpression, or point mutations, are associated with poor prognosis and advanced stage disease. Inhibition of ALK k...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Di Paolo, Daniela, Ambrogio, Chiara, Pastorino, Fabio, Brignole, Chiara, Martinengo, Cinzia, Carosio, Roberta, Loi, Monica, Pagnan, Gabriella, Emionite, Laura, Cilli, Michele, Ribatti, Domenico, Allen, Theresa M, Chiarle, Roberto, Ponzoni, Mirco, Perri, Patrizia
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242652/
https://ncbi.nlm.nih.gov/pubmed/21829174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.142
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk