Chemoresistant colorectal cancer cells and cancer stem cells mediate growth and survival of bystander cells

BACKGROUND: Recent studies suggest that cancer stem cells (CSCs) mediate chemoresistance, but interestingly, only a small percentage of cells in a resistant tumour are CSCs; this suggests that non-CSCs survive by other means. We hypothesised that chemoresistant colorectal cancer (CRC) cells generate...

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Autors principals: Bose, D, Zimmerman, L J, Pierobon, M, Petricoin, E, Tozzi, F, Parikh, A, Fan, F, Dallas, N, Xia, L, Gaur, P, Samuel, S, Liebler, D C, Ellis, L M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242606/
https://ncbi.nlm.nih.gov/pubmed/22045189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.449
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