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Significant Selective Constraint at 4-Fold Degenerate Sites in the Avian Genome and Its Consequence for Detection of Positive Selection

A major conclusion from comparative genomics is that many sequences that do not code for proteins are conserved beyond neutral expectations, indicating that they evolve under the influence of purifying selection and are likely to have functional roles. Due to the degeneracy of the genetic code, syno...

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Hlavní autoři: Künstner, Axel, Nabholz, Benoit, Ellegren, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242499/
https://ncbi.nlm.nih.gov/pubmed/22042333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evr112
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