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K(r)/K(c) but not d(N)/d(S) correlates positively with body mass in birds, raising implications for inferring lineage-specific selection

BACKGROUND: The ratio of the rates of non-synonymous and synonymous substitution (d(N)/d(S)) is commonly used to estimate selection in coding sequences. It is often suggested that, all else being equal, d(N)/d(S) should be lower in populations with large effective size (N(e)) due to increased effica...

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Détails bibliographiques
Publié dans:Genome Biol
Auteurs principaux: Weber, Claudia C, Nabholz, Benoit, Romiguier, Jonathan, Ellegren, Hans
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264323/
https://ncbi.nlm.nih.gov/pubmed/25607475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0542-8
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