FOXO3a dependent mechanism of E1A-Induced chemosensitization

Gene therapy trials in human breast, ovarian, and head and neck tumors indicate that adenovirus E1A can sensitize cancer cells to the cytotoxic effects of paclitaxel in vitro and in vivo. Resistance to paclitaxel has been reported to occur in cells expressing low levels of the Forkhead transcription...

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Bibliographic Details
Main Authors: Su, Jen-Liang, Cheng, Xiaoyun, Yamaguchi, Hirohito, Chang, Yi-Wen, Hou, Chao-Feng, Lee, Dung-Fang, Ko, How-Wen, Hua, Kuo-Tai, Wang, Ying-Nai, Hsiao, Michael, Chen, PoShen B., Hsu, Jung-Mao, Bast, Robert C., Hortobagyi, Gabriel, Hung, Mien-Chie
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242367/
https://ncbi.nlm.nih.gov/pubmed/21911455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0295
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