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Pak1 as a Novel Therapeutic Target for Anti-Hypertrophic Treatment in the Heart

BACKGROUND: Stress-induced hypertrophic remodeling is a critical pathogenetic process leading to heart failure. While many signal transduction cascades are demonstrated as important regulators to facilitate the induction of cardiac hypertrophy, the signaling pathways for suppressing hypertrophic rem...

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Hlavní autoři: Liu, Wei, Zi, Min, Naumann, Ronald, Ulm, Susanne, Jin, Jiawei, Taglieri, Domenico M., Prehar, Sukhpal, Gui, Junhong, Tsui, Hoyee, Xiao, Rui-Ping, Neyses, Ludwig, Solaro, R. John, Ke, Yunbo, Cartwright, Elizabeth J., Lei, Ming, Wang, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242076/
https://ncbi.nlm.nih.gov/pubmed/22082674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.048785
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