STRUCTURAL CHARACTERISATION OF THE LEISHMANIA MAJOR ORTHOLOGUES OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF)

Leishmania major, an intracellular parasitic protozoon that infects, differentiates and replicates within macrophages, encodes two closely related MIF-like proteins, which have only ~20% amino acid identity with mammalian MIF. Recombinant L. major MIF1 and MIF2 have been expressed and the structures...

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Main Authors: Richardson, Julia M., Morrison, Lesley S., Bland, Nicholas D., Bruce, Sandra, Coombs, Graham H., Mottram, Jeremy C., Walkinshaw, Malcolm D.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242041/
https://ncbi.nlm.nih.gov/pubmed/19187777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.01.030
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