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The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity

Chronic inflammatory diseases are characterised by systemically elevated levels of tumour necrosis factor (TNF)-α, a proinflammatory cytokine with pleiotropic downstream effects. We have previously demonstrated increased genotoxicity in peripheral leukocytes and various tissues in models of intestin...

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Detalhes bibliográficos
Main Authors: Westbrook, Aya M., Wei, Bo, Hacke, Katrin, Xia, Menghang, Braun, Jonathan, Schiestl, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241942/
https://ncbi.nlm.nih.gov/pubmed/21980144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ger063
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