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Mathematical modeling of prostate cancer progression in response to androgen ablation therapy

Prostate cancer progression depends in part on the complex interactions between testosterone, its active metabolite DHT, and androgen receptors. In a metastatic setting, the first line of treatment is the elimination of testosterone. However, such interventions are not curative because cancer cells...

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Bibliografiske detaljer
Main Authors: Jain, Harsh Vardhan, Clinton, Steven K., Bhinder, Arvinder, Friedman, Avner
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241775/
https://ncbi.nlm.nih.gov/pubmed/22106268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115750108
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