Dual role of methionyl-tRNA synthetase in the regulation of translation and tumor suppressor activity of aminoacyl-tRNA synthetase-interacting multifunctional protein-3

Mammalian methionyl-tRNA synthetase (MRS) plays an essential role in initiating translation by transferring Met to initiator tRNA (tRNA(i)(Met)). MRS also provides a cytosolic anchoring site for aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (AIMP3)/p18, a potent tumor suppressor th...

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Bibliographische Detailangaben
Hauptverfasser: Kwon, Nam Hoon, Kang, Taehee, Lee, Jin Young, Kim, Hyo Hyun, Kim, Hye Rim, Hong, Jeena, Oh, Young Sun, Han, Jung Min, Ku, Min Jeong, Lee, Sang Yeol, Kim, Sunghoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241768/
https://ncbi.nlm.nih.gov/pubmed/22106287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103922108
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