Molecular architecture of the Spire–actin nucleus and its implication for actin filament assembly

The Spire protein is a multifunctional regulator of actin assembly. We studied the structures and properties of Spire–actin complexes by X-ray scattering, X-ray crystallography, total internal reflection fluorescence microscopy, and actin polymerization assays. We show that Spire–actin complexes in...

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Bibliographic Details
Main Authors: Sitar, Tomasz, Gallinger, Julia, Ducka, Anna M., Ikonen, Teemu P., Wohlhoefler, Michael, Schmoller, Kurt M., Bausch, Andreas R., Joel, Peteranne, Trybus, Kathleen M., Noegel, Angelika A., Schleicher, Michael, Huber, Robert, Holak, Tad A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241762/
https://ncbi.nlm.nih.gov/pubmed/22106272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115465108
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