Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

The Wnt/β-catenin signaling pathway is important for tumor initiation and progression. The low density lipoprotein receptor-related protein-6 (LRP6) is an essential Wnt co-receptor for Wnt/β-catenin signaling and represents a promising anticancer target. Recently, the antihelminthic drug, niclosamid...

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Detaylı Bibliyografya
Asıl Yazarlar: Lu, Wenyan, Lin, Cuihong, Roberts, Michael J., Waud, William R., Piazza, Gary A., Li, Yonghe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241710/
https://ncbi.nlm.nih.gov/pubmed/22195040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029290
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