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Reporter mRNAs cleaved by Rnt1p are exported and degraded in the cytoplasm
For most protein coding genes, termination of transcription by RNA polymerase II is preceded by an endonucleolytic cleavage of the nascent transcript. The 3′ product of this cleavage is rapidly degraded via the 5′ exoribonuclease Rat1p which is thought to destabilize the RNA polymerase II complex. I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241649/ https://ncbi.nlm.nih.gov/pubmed/21821655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr627 |
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