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Lipopolysaccharide induces cytokine production and decreases extravillous trophoblast invasion through a mitogen-activated protein kinase-mediated pathway: possible mechanisms of first trimester placental dysfunction

BACKGROUND: Defects in extravillous trophoblast (EVT) function could contribute to placental dysfunction resulting in adverse obstetrical outcomes. Adverse obstetrical outcomes have been highly correlated with intrauterine infection; however, the mechanisms linking infection to placental dysfunction...

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Bibliographic Details
Main Authors: Anton, Lauren, Brown, Amy G., Parry, Samuel, Elovitz, Michal A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241604/
https://ncbi.nlm.nih.gov/pubmed/22052387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/der362
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