HIF-1α Stabilization Increases miR-210 Eliciting First Trimester Extravillous Trophoblast Mitochondrial Dysfunction

Preeclampsia is associated with first trimester placental dysfunction. miR-210, a small non-coding RNA, is increased in the preeclamptic placenta. The effects of elevated miR-210 on placental function remain unclear. The objectives of this study were to identify targets of miR-210 in first trimester...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Anton, Lauren, DeVine, Ann, Polyak, Erzsebet, Olarerin-George, Anthony, Brown, Amy G., Falk, Marni J., Elovitz, Michal A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590495/
https://ncbi.nlm.nih.gov/pubmed/31263422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00699
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