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A route to RNA with an alkylating group at the 5'-triphosphate residue.
Reaction of ATP with N,N,N'-tris(2-chloroethyl), N' (p-formyl-phenyl)propylenediamine-1,3 (abbreviation C13R) afforded a gamma-ester of ATP (abbreviation C1RpppA) - the product of alkylation by an aliphatic nitrogen mustard residue of C13R. The alkylating activity of the aromatic nitrogen...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1980
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC324160/ https://ncbi.nlm.nih.gov/pubmed/6160472 |
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